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        ºû¥Í¯ÀB1¯Ê¥F¤§Á{§É¼xª¬¡AÅã²{¹}®Æ±Ä­¹¶q´î§C¡A¥Íªø¤£¨}¡B¨­Å饭¿Å¤£¨}¡Bµj¡B¨xŦ·l®`¤Î¦º¤`²v°ª¡Cºû¥Í¯ÀB1¤§»Ý­n¶qÀHµÛ¹}®Æ¤¤ºÒ¤ô¤Æ¦Xª«¤§¼W¥[¦Ó¼W¥[(Tiemann»PJuerss¡A1978)¡C·í¤ô·Å¸û°ª»Pºò­¢¤§±¡ªp¤U¡A¥ç¾É­P¨ä»Ý­n¶q¼W¥[¡Cºû¥Í¯ÀB1¨ÑÀ³³Ì¦n¤§«ü¼Ð¬°transketolase¤§¬¡©Ê¡A¦]¦¹¨ä¯Ê¥F¥i¦bÁ{§É¯gª¬µo¥Í«e§Y³QÀË¥X¡CAoe (1969)§Y«üºÙ¹}®Æ¤¤¥¼²K¥[ºû¥Í¯ÀB1®É¡A¦b¸ÕÅç«á¤§¼Æ¶g¦º¤`²vÅãµÛ¼W¥[¡C¨ä¨xŦ­«¶q¥çÅãµÛ¦a¸ûºû¥Í¯ÀB1 50²@§J²K¥[²Õ¬°§C¡C·íºû¥Í¯ÀB1¯Ê¥F¤é³¤¤¡A¨C¤½¤ç¹}®Æ²K¥[50²@§J«á¼Æ¤é¡A¨ä¯Ê¥F¯gª¬§Y®ø¥¢¡C

        ¦p³½¹}¤©³½©Î³½¤§¼o±óª«¡A¥²¶·ª`·N¤j³¡¥÷²H¤ô³½¤ÎóÖ³½¨­Åé§t¦³thiminase¡C¯à¤À¸Ñºû¥Í¯ÀB1 (thiamin)¨Ã¨Ï¨äµL¬¡©Ê¡C¦]¦¹¹}®Æ¤¤¤§thiminasesÀ³¦b¹}¾i«e¥[¼ö¨Ï¤£¬¡¤Æ¡C

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        B2¯Ê¥F¤§©úÅã¼xª¬¬°­¹¼¤¤£¨Î¡BÄΡBÄλ\¡BÅ_½tÃa¦º¡A²´·ú´¹ª¬Åé¼Ò½k¤Î°ª¦º¤`²v»P¥Íªø­°§C¡C¦bøW³½ºû¥Í¯ÀB2»Ý­n¶q¤è­±¤w¦³³\¦h¸ê®Æ¡CMcLarenµ¥(1947)ÃÒ©ú¨C¤½¤ç¹}®ÆÀ³¬°5¡ã15²@§J¡AµM¦ÓPhillips (1947)«h¬ã¨sÃÒ¹ê¨C¤½¤ç¹}®Æ¤§¾A·í²K¥[¶q¬°35²@§J¡CHughesµ¥(1981)ºÙºû¥Í¯ÀB2¤§»Ý­n¶q¬°¨C¤½¤ç¹}®Æ§t3²@§J¡A¦ÓTakcuchiµ¥(1980)µo²{¨C¤½¤ç¹}®Æ§t6²@§J®É¨x¤¤¤§¶J¦s¶q³Ì°ª¡CWoodward (1985)¥çÃÒ©ú¦b¤é³§t40¢H¤§²Ê³J¥Õ½è®É¡A¨C¤½¤ç¹}®ÆB2¤§³Ì¤j»Ý­n¶q¬°6.6²@§J¡A¦¹¤w¦b¦UºØ±¡ªp¤U¥[¥H½T©w¡C¦b­iøW¨C¤½¤ç¹}®Æ¹L¶q²K¥[¦Ü600²@§J®É¡A¹ï¥Íªø¨ÃµL¤£¨}¼vÅT(Hughes 1984)¡C

(3)ºû¥Í¯ÀB6

        ºû¥Í¯ÀB6¬°³J¥Õ½è¥NÁ¤¤¤ß¦ì¸m¤§»²úA¡C¯Ê¥Fºû¥Í¯ÀB6¤§©úÅãÁ{§É¼xª¬¬°Åöú@©Êµj¡B©I§l¥[³t¡B°ª¦º¤`²v¤Î«æ³t¦º¤`¡C

        ¨ä¦b³J¥Õ½è¥NÁ¤§¥\¯à¤è­±¡AÅãµMªº¡A³½±Ä­¹¸û°ª³J¥Õ½è»P§ïµ½¥ÍÅé­«¤§±¡ªp¤U¡Aºû¥Í¯ÀB6¤§»Ý­n¶q¥ç¼W¥[¡CPhillips»PBrockway (1957)µo²{¦UºØÂD³½¨C¤½¤çÅé­«©Î¨C¤éºû¥Í¯ÀB6¤§»Ý­n¶q¬°0.225¡ã0.250²@§J¡C¦b±Ä­¹¶q¬°Åé­«¤§2¢H®É¡A¥i¥Ñ¦¹±À½×¬°¨C¤½¤ç¹}®Æ¬°12²@§J¡CLeithµ¥(1985)µo²{¨C¤½¤ç¹}®Æ§t15²@§J¤§B6§Y¨¬°÷´£¨Ñ¾A·í¤§¥Íªø»P¹}®Æ§Q¥Î²v¡C

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        ¯Ê¥F¼xª¬Åã¥Ü¥Íªø´î°h¡B­¹¼¤´î§C¡BÄθ~µÈ»PÖߵۤદº¤`²v¡C¥Ñ¦b¨xŦ¤¤³Ì¤j¶J¦s¶q¦Ó¨¥¡APhillips (1949)±Àºâ¨C¤½¤çÅé­«»P¨C¤Ñ¤§»Ý­n¶q¬°0.97¡ã1.25²@§J¡C¦¹¬Û·í©ó¨C¤½¤ç¹}®Æ§t50¡ã60²@§J¡CKarges»PWoodward (1984)¥H§t¡C©Î40²@§Jªx»Ä¤§¥b¦X¦¨¤é³¹}³½¡A¨ä¯Ê¥F¼xª¬¥i¥Ñ²K¥[¦Ó§¹¥þ§K°£¡C

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        Á{§É¯Ê¥F¼xª¬Åã¥Ü¥Íªø¿ð½w¡B­¹¼¤´î°h¡B¹}®Æ§Q¥Î²v¤£¨Î¡B¥Ö½§¨ü·l¤Î³h¦å¡C¨Ì¾ÚPoston»PCombs (1980)ºÙÂD³½ÃþµLªk¦³®Ä¦a§Q¥Î¹}®Æ¤¤¤§¦âÓi»Ä°µ¬°µÒÆP»Ä¤§«eÅXª«¡C¦b¹ê¥Î¤W¨C¤½¤ç¹}®Æ²K¥[¶W¹L100²@§J¤wÃÒ©ú¬O¾A·íªº¡C

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        °²¨Ï¤é³¤¤§t°ª¶q¤§³½¯»¡A«h¥Íª«¯À·¥¤Ö¯Ê¥F¡CCastledineµ¥(1978)¥H§t³½¯»¤§¹}®Æ¨C¤½¤ç²K¥[250¡ã500©Î1000ug¹}³½¡Aµo²{¦UºØ§t¶q¤§¶¡¨ä¥Íªø¨ÃµL®t²§¡C¦ý¹}®Æ¤¤§t¸û°ª¶qªÌ¡A¨ä¨xŦ¤¤¤§¥Íª«¯À¿@«×¤Wª@¡C°²¨Ï¤é³¤¤ºÒ¤ô¤Æ¦Xª«§t¶q°ª®É¡A«h¥[¼@¥Íª«¯À¤§¯Ê¥F¡A¦¹¥ÑWaltonµ¥(1985)¬ã¨sÅã¥Ü¥H§t¦³©Î¤£§t¾ý¯»¡A¨Ã¤À§O¨C¤½¤ç¹}®Æ²K¥[¡C©Î5²@§J¤§¥Íª«¯À¹}¾i¦ÓÀò±oÃÒ¹ê¡CÁöµM¥¼²K¥[¥Íª«¯ÀªÌ¨ÃµL¨å«¬¤§¯Ê¥F¼xª¬¡A¦ý¥Íªø»P¹}®Æ§Q¥Î®Ä²v´X¥G´î¥b¡C

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        ¹}®Æ¤¤²K¥[ºû¥Í¯ÀB12¤§¶q½T©w¡A¦]µLªk½T©w¦UºØ³½¸z¹D¤¤¤§·L¥Íª«¯à¦X¦¨¦h¤Ö¶q¤§ºû¥Í¯ÀB12¡C¤£¦P¾A·í§t¶q¤§¹W¥i¥Î©ó³½¹ïºû¥Í¯ÀB12¤§¦X¦¨¡C³½¹}®Æ¤¤¨C¤½¤ç²K¥[30¡ã40ug¤§ºû¥Í¯ÀB12¡A¥i¥H§ïµ½­iøW¥®­]»P¥®³½¤§¥Íªø(Trofimova, 1962)¡C

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        ¯Ê¥F¼xª¬ÀHµÛ³½Åé­«¤§¼W¥[¦Ó¥X²{¡C·í¥®³½¹}¤©¯Ê¥Fºû¥Í¯ÀC¤§¤é³¡A¨ä©úÅ㤧¼xª¬¦b¨äÅé­«¼W¥[10­¿«á¥X²{¡C¤ô·Å¥ç¼vÅTºû¥Í¯ÀC¯Ê¥F«á¯Ê¥F¼xª¬¥X²{¤§®É¶¡¡C¦b¸û°ª¤ô·Å¤U¡A¨ä¯Ê¥F¼xª¬¥X²{¸û§Ö(Halrerµ¥1975)¡C¨Ì¾ÚTucker»PHalver (1984)ºÙ§ÜÃa¦å»Ä¡Ð2¡Ð²¸»ÄÆQ¬°øW³½ºû¥Í¯ÀC¤§¥D­n¶J¦s§Î¦¡¡A·í»Ý­n®É¡A©ó¤¤¶¡¥NÁÂÂàÅܦ¨ºû¥Í¯ÀC¡C

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